More Than Two HANDs to Tango

Two Hands Are Better Than One (up to constant factors)

We study the difference between the standard seeded model of tile self-assembly, and the “seedless” two-handed model of tile self-assembly. Most of our results suggest that the two-handed model is more powerful. In particular, we show how to simulate any seeded system with a two-handed system that is essentially just a constant factor larger. We exhibit finite shapes with a busy-beaver separati...

It takes two to tango

The vertebrate inner ear has time and again surprised neurobiologists by adding new wrinkles to known mechanisms of cellular signaling. among those surprises, was the discovery that nicotinic acetylcholine receptors (related to those that excite muscle) inhibit cochlear hair cells when acetylcholine (aCh) is released from efferent neurons. Inhibition occurs because calcium entering through the ...

Emotive characters can make learning more productive and enjoyable: It takes two to learn to tango

In this paper we explore a new direction for pedagogical computer agents, also called computer characters, which we believe will maximize students’ learning gains and enjoyment. To the traditional scenario where students interact primarily with a single coach or tutor character on-screen, we introduce the addition of both a social, animate colearner, and the student’s own avatar character. Vari...

Comparing More Than Two Groups

Does It Take Two to Tango?

The debate continues regarding the existence of an adverse interaction between proton pump inhibitors (PPIs) and clopidogrel. Concerns for a drug-drug interaction first emerged when experimental pharmacodynamic data indicated that omeprazole might diminish the in vitro antiplatelet effects of clopidogrel.1,2 These concerns were escalated when retrospective data from 2 large observational studie...